Abstract
A discussion of matching, randomization, random sampling, and other methods of controlling extraneous variation is presented. The objective is to specify the benefits of randomization in estimating causal effects of treatments. The basic conclusion is that randomization should be employed whenever possible but that the use of carefully controlled nonrandomized data to estimate causal effects is a reasonable and necessary procedure in many cases. Recent psychological and educational literature has included extensive criticism of the use of nonrandomized studies to estimate causal effects of treatments (e.g., Campbell & Erlebacher, 1970). The implication in much of this literature is that only properly randomized experiments can lead to useful estimates of causal effects. If taken as applying to all fields of study, this position is untenable. Since the extensive use of randomized experiments is limited to the last half century,8 and in fact is not used in much scientific investigation today,4 one is led to the conclusion that most scientific truths have been established without using randomized experiments. In addition, most of us successfully determine the causal effects of many of our everyday actions, even interpersonal behaviors, without the benefit of randomization. Even if the position that causal effects of treatments can only be well established from randomized experiments is taken as applying only to the social sciences in which
Keywords
Affiliated Institutions
Related Publications
The Magic of Randomization versus the Myth of Real-World Evidence
Nonrandomized observational analyses have been promoted as alternatives to randomized clinical trials. However, randomization ensures balance between groups, whereas nonrandomiz...
The many weak instruments problem and Mendelian randomization
Instrumental variable estimates of causal effects can be biased when using many instruments that are only weakly associated with the exposure. We describe several techniques to ...
Random Allocation in Observational Data
Conventional observational epidemiology has an unenviable reputation for generating false-positive findings,1,2 or "scares," as others call them.3 In 1993, for example, the New ...
Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
Abstract Observational epidemiological studies suffer from many potential biases, from confounding and from reverse causation, and this limits their ability to robustly identify...
The Mixed Methods Appraisal Tool (MMAT) version 2018 for information professionals and researchers
Introduction: Appraising the quality of studies included in systematic reviews combining qualitative, quantitative and mixed methods studies is challenging. To address this chal...
Publication Info
- Year
- 1974
- Type
- article
- Volume
- 66
- Issue
- 5
- Pages
- 688-701
- Citations
- 9061
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1037/h0037350