Abstract

Microfluidic devices for manipulating fluids are widespread and finding uses in many scientific and industrial contexts. Their design often requires unusual geometries and the interplay of multiple physical effects such as pressure gradients, electrokinetics, and capillarity. These circumstances lead to interesting variants of well-studied fluid dynamical problems and some new fluid responses. We provide an overview of flows in microdevices with focus on electrokinetics, mixing and dispersion, and multiphase flows. We highlight topics important for the description of the fluid dynamics: driving forces, geometry, and the chemical characteristics of surfaces.

Keywords

MicrofluidicsElectrokinetic phenomenaFluid dynamicsMixing (physics)NanotechnologyFocus (optics)Fluid mechanicsMechanicsLab-on-a-chipMultiphase flowComputer scienceMaterials sciencePhysicsOptics

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Publication Info

Year
2003
Type
article
Volume
36
Issue
1
Pages
381-411
Citations
3497
Access
Closed

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Howard A. Stone, Abraham D. Stroock, Armand Ajdari (2003). Engineering Flows in Small Devices: Microfluidics Toward a Lab-on-a-Chip. Annual Review of Fluid Mechanics , 36 (1) , 381-411. https://doi.org/10.1146/annurev.fluid.36.050802.122124

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DOI
10.1146/annurev.fluid.36.050802.122124