Abstract
This tutorial review presents recent developments of homochiral metal-organic frameworks (MOFs) in enantioselective catalysis. Following a brief introduction of the basic concepts and potential virtues of MOFs in catalysis, we summarize three distinct strategies that have been utilized to synthesize homochiral MOFs. Framework stability and accessibility of the open channels to reagents are then addressed. We finally survey recent successful examples of catalytically active homochiral MOFs based on three approaches, namely, homochiral MOFs with achiral catalytic sites, incorporation of asymmetric catalysts directly into the framework, and post-synthetic modification of homochiral MOFs. Although still in their infancy, homochiral MOFs have clearly demonstrated their utility in heterogeneous asymmetric catalysis, and a bright future is foreseen for the development of practically useful homochiral MOFs in the production of optically pure organic molecules.
Keywords
Enantioselective synthesisMetal-organic frameworkCatalysisChemistryOrganic synthesisCombinatorial chemistryNanotechnologyOrganic chemistryMaterials science
Affiliated Institutions
Related Publications
A General Thermolabile Protecting Group Strategy for Organocatalytic Metal−Organic Frameworks
We present a general strategy for incorporating organocatalytic moieties into metal-organic frameworks (MOFs). The organocatalytic units are protected by a thermolabile protecti...
A Homochiral Porous Metal−Organic Framework for Highly Enantioselective Heterogeneous Asymmetric Catalysis
A homochiral porous noninterpenetrating metal-organic framework (MOF), 1, was constructed by linking infinite 1D [Cd(mu-Cl)2]n zigzag chains with axially chiral bipyridine bridg...
Postsynthetic modification of metal–organic frameworks
The modification of metal-organic frameworks (MOFs) in a postsynthetic scheme is discussed in this critical review. In this approach, the MOF is assembled and then modified with...
Metal–Organic Framework-Based Catalysts with Single Metal Sites
Metal-organic frameworks (MOFs) are a class of distinctive porous crystalline materials constructed by metal ions/clusters and organic linkers. Owing to their structural diversi...
Stable Metal–Organic Frameworks: Design, Synthesis, and Applications
Abstract Metal–organic frameworks (MOFs) are an emerging class of porous materials with potential applications in gas storage, separations, catalysis, and chemical sensing. Desp...
Publication Info
- Year
- 2009
- Type
- review
- Volume
- 38
- Issue
- 5
- Pages
- 1248-1248
- Citations
- 3092
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
3092
OpenAlex
Cite This
Liqing Ma,
Carter W. Abney,
Wenbin Lin
(2009).
Enantioselective catalysis with homochiral metal–organic frameworks.
Chemical Society Reviews
, 38
(5)
, 1248-1248.
https://doi.org/10.1039/b807083k
Identifiers
- DOI
- 10.1039/b807083k