Affiliated Institutions
Related Publications
CTCF-dependent enhancer-blocking by alternative chromatin loop formation
The mechanism underlying enhancer-blocking by insulators is unclear. We explored the activity of human β-globin HS5, the orthologue of the CTCF-dependent chicken HS4 insulator. ...
Pyrazole Urea-Based Inhibitors of p38 MAP Kinase: From Lead Compound to Clinical Candidate
We report on a series of N-pyrazole, N'-aryl ureas and their mode of binding to p38 mitogen activated protein kinase. Importantly, a key binding domain that is distinct from the...
Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations
Mutations in the p53 tumor suppressor are the most frequently observed genetic alterations in human cancer. The majority of the mutations occur in the core domain which contains...
PROMOTIF—A program to identify and analyze structural motifs in proteins
Abstract We describe a suite of programs, PROMOTIF, that analyzes a protein coordinate file and provides details about the structural motifs in the protein. The program currentl...
Refinement of the structure of β‐chitin
Abstract The structure of β‐chitin has been refined by rigid‐body least‐squares methods, based on the intensity data for highly crystalline specimens from the pogonophore Oligob...
Publication Info
- Year
- 2025
- Type
- peer-review
- Citations
- 0
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
0
OpenAlex
Cite This
Toby W. Allen
(2025).
eLife Assessment: Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase.
.
https://doi.org/10.7554/elife.107688.2.sa3
Identifiers
- DOI
- 10.7554/elife.107688.2.sa3