Abstract
Evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-based energy, with increased stress resistance, increased longevity, and a decreased incidence of diseases, including cancer and obesity.
Keywords
MedicineLongevityObesityIncidence (geometry)Intermittent fastingDiseaseInternal medicineInsulin resistanceKetone bodiesEndocrinologyPhysiologyGerontologyMetabolism
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Publication Info
- Year
- 2019
- Type
- review
- Volume
- 381
- Issue
- 26
- Pages
- 2541-2551
- Citations
- 1405
- Access
- Closed
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Cite This
Rafael de Cabo,
Mark P. Mattson
(2019).
Effects of Intermittent Fasting on Health, Aging, and Disease.
New England Journal of Medicine
, 381
(26)
, 2541-2551.
https://doi.org/10.1056/nejmra1905136
Identifiers
- DOI
- 10.1056/nejmra1905136