Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus

Abstract

The combination of fenofibrate and simvastatin did not reduce the rate of fatal cardiovascular events, nonfatal myocardial infarction, or nonfatal stroke, as compared with simvastatin alone. These results do not support the routine use of combination therapy with fenofibrate and simvastatin to reduce cardiovascular risk in the majority of high-risk patients with type 2 diabetes. (ClinicalTrials.gov number, NCT00000620.)

Keywords

MedicineFenofibrateHazard ratioInternal medicineSimvastatinFibrateDiabetes mellitusPlaceboMyocardial infarctionType 2 Diabetes MellitusStatinType 2 diabetesConfidence intervalStroke (engine)Endocrinology

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Publication Info

Year: 2010
Type: article
Volume: 362
Issue: 17
Pages: 1563-1574
Citations: 2773
Access: Closed

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APA Style

                            
                                
                                    Henry N. Ginsberg, 
                                
                                    Marshall B. Elam, 
                                
                                    Laura Lovato
                                
                                et al.
                            
                            (2010). 
                            Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus. 
                            New England Journal of Medicine
                            , 362
                            (17)
                            , 1563-1574.
                            https://doi.org/10.1056/nejmoa1001282
                        

Identifiers

DOI: 10.1056/nejmoa1001282