Effects of Calcium-Channel Blockade in Older Patients with Diabetes and Systolic Hypertension

Jaakko Tuomilehto; Daiva Rastenytė; W. H. Birkenhäger; Lutgarde Thijs; Riitta Antikaínen; Christopher J. Bulpitt; Astrid Fletcher; Françoise Forette; Adiv Goldhaber; Paolo Palatini; Cinzia Sarti; Jan A. Staessen; Robert Fagard

doi:10.1056/nejm199903043400902

Abstract

Nitrendipine-based antihypertensive therapy is particularly beneficial in older patients with diabetes and isolated systolic hypertension. Thus, our findings do not support the hypothesis that the use of long-acting calcium-channel blockers may be harmful in diabetic patients.

Keywords

MedicineNitrendipineBlood pressureDiabetes mellitusEnalaprilCalcium channel blockerHydrochlorothiazidePlaceboDiastoleInternal medicineRandomizationDiureticSystolic hypertensionCardiologyMicroalbuminuriaRandomized controlled trialEndocrinologyAngiotensin-converting enzyme

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Publication Info

Year: 1999
Type: article
Volume: 340
Issue: 9
Pages: 677-684
Citations: 945
Access: Closed

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APA Style

                            
                                
                                    Jaakko Tuomilehto, 
                                
                                    Daiva Rastenytė, 
                                
                                    W. H. Birkenhäger
                                
                                et al.
                            
                            (1999). 
                            Effects of Calcium-Channel Blockade in Older Patients with Diabetes and Systolic Hypertension. 
                            New England Journal of Medicine
                            , 340
                            (9)
                            , 677-684.
                            https://doi.org/10.1056/nejm199903043400902
                        

Identifiers

DOI: 10.1056/nejm199903043400902