Effectiveness and Cost of Olanzapine and Haloperidol in the Treatment of Schizophrenia<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>

2003 JAMA 315 citations

Abstract

Olanzapine does not demonstrate advantages compared with haloperidol (in combination with prophylactic benztropine) in compliance, symptoms, extrapyramidal symptoms, or overall quality of life, and its benefits in reducing akathisia and improving cognition must be balanced with the problems of weight gain and higher cost.

Keywords

OlanzapineMedicineVeterans AffairsAkathisiaSchizoaffective disorderSchizophrenia (object-oriented programming)PsychiatryRandomized controlled trialHaloperidolTardive dyskinesiaAntipsychoticExtrapyramidal symptomsNeurocognitiveAdverse effectRandomizationInternal medicinePsychosisCognition

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Year
2003
Type
article
Volume
290
Issue
20
Pages
2693-2693
Citations
315
Access
Closed

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Robert A. Rosenheck (2003). Effectiveness and Cost of Olanzapine and Haloperidol in the Treatment of Schizophrenia<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>. JAMA , 290 (20) , 2693-2693. https://doi.org/10.1001/jama.290.20.2693

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DOI
10.1001/jama.290.20.2693