Effect of Partial Ileal Bypass Surgery on Mortality and Morbidity from Coronary Heart Disease in Patients with Hypercholesterolemia

Hēnry Buchwald; Richard L. Varco; John P. Matts; John M. Long; Laurie L. Fitch; Gilbert S. Campbell; Malcolm B. Pearce; Albert E. Yellin; W.Allan Edmiston; Robert D. Smink; Henry S. Sawin; Christian T. Campos; Betty J. Hansen; Naip Tuna; James N. Karnegis; Miguel E. Sanmarco; Kurt Amplatz; W R Castańeda-Zúńiga; David W. Hunter; Joseph K. Bissett; Frederic J. Weber; James Stevenson; Arthur S. Leon; Thomas C. Chalmers

doi:10.1056/nejm199010043231404

Abstract

Partial ileal bypass produces sustained improvement in the blood lipid patterns of patients who have had a myocardial infarction and reduces their subsequent morbidity due to coronary heart disease. The role of this procedure in the management of hypercholesterolemia remains to be determined. These results provide strong evidence supporting the beneficial effects of lipid modification in the reduction of atherosclerosis progression.

Keywords

MedicineBypass surgeryHyperlipidemiaMyocardial infarctionSurgeryRandomized controlled trialInternal medicinePopulationMortality rateCoronary heart diseaseCardiologyDiabetes mellitusArtery

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Publication Info

Year: 1990
Type: article
Volume: 323
Issue: 14
Pages: 946-955
Citations: 1008
Access: Closed

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APA Style

                            
                                
                                    Hēnry Buchwald, 
                                
                                    Richard L. Varco, 
                                
                                    John P. Matts
                                
                                et al.
                            
                            (1990). 
                            Effect of Partial Ileal Bypass Surgery on Mortality and Morbidity from Coronary Heart Disease in Patients with Hypercholesterolemia. 
                            New England Journal of Medicine
                            , 323
                            (14)
                            , 946-955.
                            https://doi.org/10.1056/nejm199010043231404
                        

Identifiers

DOI: 10.1056/nejm199010043231404