Abstract
Repression of E6 and E7 oncogenes results in restoration of p53 and pRb suppressor pathways and induced apoptosis in HPV16-positive oropharyngeal squamous cell cancer cell lines.
Keywords
Small hairpin RNAMolecular biologyBiologyGene silencingOncogeneApoptosisCell cultureRetinoblastoma proteinGeneCancer researchCell cycleRNAGenetics
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Publication Info
- Year
- 2009
- Type
- article
- Volume
- 101
- Issue
- 6
- Pages
- 412-423
- Citations
- 263
- Access
- Closed
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Cite This
Θεόδωρος Ράμπιας,
Clarence T. Sasaki,
Paul Weinberger
et al.
(2009).
E6 and E7 Gene Silencing and Transformed Phenotype of Human Papillomavirus 16-Positive Oropharyngeal Cancer Cells.
JNCI Journal of the National Cancer Institute
, 101
(6)
, 412-423.
https://doi.org/10.1093/jnci/djp017
Identifiers
- DOI
- 10.1093/jnci/djp017