Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”

Abstract

Abstract New diagnostic criteria for multiple sclerosis integrating magnetic resonance image assessment with clinical and other paraclinical methods were introduced in 2001. The “McDonald Criteria” have been extensively assessed and used since 2001. New evidence and consensus now strengthen the role of these criteria in the multiple sclerosis diagnostic workup to demonstrate dissemination of lesions in time, to clarify the use of spinal cord lesions, and to simplify diagnosis of primary progressive disease. The 2005 Revisions to the McDonald Diagnostic Criteria for MS should simplify and speed diagnosis, whereas maintaining adequate sensitivity and specificity. Ann Neurol 2005

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Affiliated Institutions

• National Multiple Sclerosis Society US
• Foothills Medical Centre CA
• Centre Hospitalier Universitaire de Rennes FR
• Heinrich Heine University Düsseldorf DE
• St. Michael's Hospital CA
• Mayo Clinic US
• National Institute of Neurological Disorders and Stroke US
• University Hospital of Basel CH
• San Raffaele University of Rome IT
• Icahn School of Medicine at Mount Sinai US
• The University of Texas Health Science Center at Houston US
• University of Amsterdam NL

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