Development of small-molecule probes that selectively kill cells induced to express mutant RAS

Michel Weïwer; Joshua A. Bittker; Timothy A. Lewis; Kaoru Shimada; Wan Seok Yang; Lawrence MacPherson; Sivaraman Dandapani; Michelle Palmer; Brent R. Stockwell; Stuart L. Schreiber; Benito Muñoz

doi:10.1016/j.bmcl.2011.09.047

Keywords

PubChemSmall moleculeOncogeneChemistryMutantCell cultureHigh-throughput screeningPhenotypic screeningChemical biologyChemical libraryCancer cellDrug discoveryComputational biologyBiochemistryCell biologyCellCancerBiologyPhenotypeGeneGeneticsCell cycle

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Publication Info

Year: 2011
Type: article
Volume: 22
Issue: 4
Pages: 1822-1826
Citations: 224
Access: Closed

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APA Style

                            
                                
                                    Michel Weïwer, 
                                
                                    Joshua A. Bittker, 
                                
                                    Timothy A. Lewis
                                
                                et al.
                            
                            (2011). 
                            Development of small-molecule probes that selectively kill cells induced to express mutant RAS. 
                            Bioorganic & Medicinal Chemistry Letters
                            , 22
                            (4)
                            , 1822-1826.
                            https://doi.org/10.1016/j.bmcl.2011.09.047
                        

Identifiers

DOI: 10.1016/j.bmcl.2011.09.047