Abstract

For patients with metastatic HNSCC, detection of HPV-16 is a reliable way to establish origin from the oropharynx, either directly by ISH or indirectly by immunohistochemistry for p16 overexpression.

Keywords

ImmunohistochemistryLymph nodeHead and neck squamous-cell carcinomaMedicineIn situ hybridizationPathologyLymphHuman papillomavirusPrimary tumorOncologyCancer researchCancerMetastasisInternal medicineHead and neck cancerBiologyGene expressionGene

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Publication Info

Year
2003
Type
article
Volume
9
Issue
17
Pages
6469-75
Citations
311
Access
Closed

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Shahnaz Begum, Maura L. Gillison, M. Ali Ansari‐Lari et al. (2003). Detection of human papillomavirus in cervical lymph nodes: a highly effective strategy for localizing site of tumor origin.. PubMed , 9 (17) , 6469-75.