Detection of adverse drug reactions in a clinical trial using two types of questioning.

Johan Wallin; Jan Sjövall

Abstract

Two methods of assessing adverse drug effects-an open-ended question versus a checklist-were compared in a clinical study involving 515 patients being treated with bacampicillin for gonorrhea. Results indicate that adverse reactions are reported more frequently if a checklist is used. However, it was also observed that more serious side effects are usually reported in response to an open-ended question rather than a checklist. Thus it was concluded that the optimal procedure for assessing adverse reactions is to record responses to both an open-ended question and a checklist.

Keywords

ChecklistMedicineAdverse effectDrug reactionClinical trialDrugOpen labelGonorrheaAdverse drug reactionIntensive care medicineInternal medicinePharmacologyFamily medicine

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Publication Info

Year: 1981
Type: article
Volume: 3
Issue: 6
Pages: 450-2
Citations: 24
Access: Closed

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APA Style

                            
                                    Johan Wallin, 
                                
                                    Jan Sjövall
                                
                            (1981). 
                            Detection of adverse drug reactions in a clinical trial using two types of questioning.. 
                            PubMed
                            , 3
                            (6)
                            , 450-2.