Abstract
Cytidine deaminase in human white blood cells has three electrophoretic phenotypes representing the homozygous and heterozygous expression of two common alleles, CDA1 and CDA2, at an autosomal locus. To explain the multibanded pattern of the heterozygote, the enzyme is assumed to have a tetrameric structure.
Keywords
Cytidine deaminaseHeterozygote advantageLocus (genetics)AlleleBiologyPhenotypeGeneticsMolecular biologyLoss of heterozygosityCytidineCompound heterozygosityEnzymeGeneBiochemistry
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Publication Info
- Year
- 1975
- Type
- article
- Volume
- 27
- Issue
- 4
- Pages
- 492-7
- Citations
- 24
- Access
- Closed
External Links
Citation Metrics
24
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Cite This
Yanting Teng,
Jeanne E. Anderson,
E.R. Giblett
(1975).
Cytidine deaminase: a new genetic polymorphism demonstrated in human granulocytes..
Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)
, 27
(4)
, 492-7.