Abstract

The primary function of the skin is to serve as a protective barrier against the environment. Loss of the integrity of large portions of the skin as a result of injury or illness may lead to major disability or even death. Every year in the United States more than 1.25 million people have burns1 and 6.5 million have chronic skin ulcers caused by pressure, venous stasis, or diabetes mellitus.2 The primary goals of the treatment of wounds are rapid wound closure and a functional and aesthetically satisfactory scar. Recent advances in cellular and molecular biology have greatly expanded our understanding . . .

Keywords

MedicineWound healingWound closureIntensive care medicineDermatologyDiabetes mellitusVenous stasisSurgery

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Year
1999
Type
review
Volume
341
Issue
10
Pages
738-746
Citations
5983
Access
Closed

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Adam J. Singer, Richard A.F. Clark (1999). Cutaneous Wound Healing. New England Journal of Medicine , 341 (10) , 738-746. https://doi.org/10.1056/nejm199909023411006

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DOI
10.1056/nejm199909023411006