Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

Dora Pinto , Young‐Jun Park , Martina Beltramello , Dora Pinto , Young‐Jun Park , Martina Beltramello , Alexandra C. Walls , M. Alejandra Tortorici , Siro Bianchi , Stefano Jaconi , Katja Culap , Fabrizia Zatta , Anna De Marco , Alessia Peter , Barbara Guarino , Roberto Spreafico , Elisabetta Cameroni , James Brett Case , Rita E. Chen , Colin Havenar‐Daughton , Gyorgy Snell , Amalio Telenti , Herbert W. Virgin , Antonio Lanzavecchia , Michael Diamond , Katja Fink , David Veesler , Davide Corti
2020 Nature 2,086 citations

Keywords

VirologyMonoclonal antibodyAntibodyNeutralizationEpitopeCoronavirusGlycoproteinBiologyPandemicSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirusImmunologyMedicineCoronavirus disease 2019 (COVID-19)DiseaseMolecular biologyInfectious disease (medical specialty)

MeSH Terms

Angiotensin-Converting Enzyme 2AnimalsAntibodiesMonoclonalAntibodiesNeutralizingAntibodiesViralAntibody-Dependent Cell CytotoxicityB-LymphocytesBetacoronavirusCOVID-19Chlorocebus aethiopsCoronavirus InfectionsCross ReactionsCryoelectron MicroscopyEpitopesB-LymphocyteHEK293 CellsHumansImmune EvasionImmunoglobulin Fab FragmentsImmunologic MemoryKiller CellsNaturalModelsMolecularNeutralization TestsPandemicsPeptidyl-Dipeptidase APneumoniaViralSevere acute respiratory syndrome-related coronavirusSARS-CoV-2Severe Acute Respiratory SyndromeSpike GlycoproteinCoronavirusVero Cells

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Publication Info

Year
2020
Type
article
Volume
583
Issue
7815
Pages
290-295
Citations
2086
Access
Closed

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Cite This

Dora Pinto, Young‐Jun Park, Martina Beltramello et al. (2020). Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody. Nature , 583 (7815) , 290-295. https://doi.org/10.1038/s41586-020-2349-y

Identifiers

DOI
10.1038/s41586-020-2349-y
PMID
32422645

Data Quality

Data completeness: 72%