Convection-enhanced delivery and systemic mannitol increase gene product distribution of AAV vectors 5, 8, and 9 and increase gene product in the adult...

Keywords

Gene deliveryGenetic enhancementViral vectorDistribution (mathematics)Adeno-associated virusHippocampusGene productVector (molecular biology)Systemic administrationParenchymaBiologyGeneGene expressionMedicinePharmacologyPathologyNeuroscienceRecombinant DNAIn vivoBiochemistryGenetics

Affiliated Institutions

Related Publications

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

Angelo Lombardo , Pietro Genovese , Christian Beauséjour +9 more

2007 Nature Biotechnology 839 citations

Scientific rationale for the development of gene therapy strategies for Parkinson's disease

Tomas Björklund , Deniz Kirik

2009 Biochimica et Biophysica Acta (BBA) -... 36 citations

Cytokine release syndrome in severe COVID-19

John B. Moore , Carl H. June

Lessons from arthritis and cell therapy in cancer patients point to therapy for severe disease

2020 Science 1984 citations

Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy

André Larochelle , Josef Vormoor , Helmut Hanenberg +9 more

1996 Nature Medicine 769 citations

Stem cell therapy and gene transfer for regeneration

Takayuki Asahara , Christoph Kalka , Jeffrey M. Isner

The committed stem and progenitor cells have been recently isolated from various adult tissues, including hematopoietic stem cell, neural stem cell, mesenchymal stem cell and en...

2000 Gene Therapy 194 citations

Publication Info

Year: 2010
Type: article
Volume: 194
Issue: 1
Pages: 144-153
Citations: 94
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Convection-enhanced delivery and systemic mannitol increase gene product distribution of AAV vectors 5, 8, and 9 and increase gene product in the adult mouse brain

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

OpenAlex

Cite This

APA Style

                            
                                
                                    Nikisha Carty, 
                                
                                    Daniel C. Lee, 
                                
                                    Chad A. Dickey
                                
                                et al.
                            
                            (2010). 
                            Convection-enhanced delivery and systemic mannitol increase gene product distribution of AAV vectors 5, 8, and 9 and increase gene product in the adult mouse brain. 
                            Journal of Neuroscience Methods
                            , 194
                            (1)
                            , 144-153.
                            https://doi.org/10.1016/j.jneumeth.2010.10.010
                        

Identifiers

DOI: 10.1016/j.jneumeth.2010.10.010