Complementation of dominant suppression implicates CD98 in integrin activation

Keywords

IntegrinIntegrinbeta 6CD49cIntegrin alpha MCell biologyCollagen receptorCell adhesionBiologyCytoplasmTransmembrane proteinSignal transductionReceptorCellGenetics

Affiliated Institutions

Related Publications

Characterization of the integrin alpha v beta 6 as a fibronectin-binding protein.

Morten Busk , Robert Pytela , Dean Sheppard

Integrins are a complex family of divalent cation-dependent cell adhesion receptors composed of one alpha and one beta subunit noncovalently bound to one another. A subset of in...

1992 Journal of Biological Chemistry 290 citations

Constitutive and stimulus-induced phosphorylation of CD11/CD18 leukocyte adhesion molecules.

Talal A. Chatila , Raif S. Geha , M. Amin Arnaout

The leukocyte CD11/CD18 adhesion molecules (beta 2 integrins) are a family of three heterodimeric glycoproteins each with a distinct alpha subunit (CD11a, b, or c) and a common ...

1989 The Journal of Cell Biology 214 citations

T cell receptor-dependent, antigen-specific stimulation of a murine T cell clone induces a transient, VLA protein-mediated binding to extracellular matrix

B M Chan , J G Wong , Arvind Rao +1 more

Abstract Upon Ag stimulation, an arsonate-specific murine T cell clone exhibited a rapid but transient increase in cell adhesion to collagen, fibronectin, and laminin. This incr...

1991 The Journal of Immunology 124 citations

The major laminin receptor of mouse embryonic stem cells is a novel isoform of the alpha 6 beta 1 integrin.

Helen Cooper , Richard N. Tamura , Vito Quaranta

Laminin is the first extracellular matrix protein expressed in the developing mouse embryo. It is known to influence morphogenesis and affect cell migration and polarization. Se...

1991 The Journal of Cell Biology 160 citations

Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins.

Eric J. Brown , Lora V. Hooper , Thang Vinh Ho +1 more

Phagocytosis by monocytes or neutrophils can be enhanced by interaction with several proteins or synthetic peptides containing the Arg-Gly-Asp sequence. Recently we showed that ...

1990 The Journal of Cell Biology 405 citations

Publication Info

Year: 1997
Type: article
Volume: 390
Issue: 6655
Pages: 81-85
Citations: 288
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Complementation of dominant suppression implicates CD98 in integrin activation

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

288

OpenAlex

Cite This

APA Style

                            
                                
                                    Csilla A. Fenczik, 
                                
                                    Tariq Sethi, 
                                
                                    Joe W. Ramos
                                
                                et al.
                            
                            (1997). 
                            Complementation of dominant suppression implicates CD98 in integrin activation. 
                            Nature
                            , 390
                            (6655)
                            , 81-85.
                            https://doi.org/10.1038/36349
                        

Identifiers

DOI: 10.1038/36349