Abstract
Abstract Although the genetic information of each cell in a yeast colony is identical, the transcriptional patterns of individual cells within that colony may be very different. These variable, or epigenetic, transcriptional patterns arise at least in part from local differences in chromatin structure. The focus of this chapter is a discussion of how chromatin structure contributes to epigenetic transcriptional states. We begin with a brief description of how chromatin structure contributes to transcriptional regulation in multicellular eukaryotes, particularly the form of regulation known as position effect variegation (a topic considered in depth in Chapter 8). We then move on to consider in greater detail the role of chromatin structure in position effect transcriptional regulation in yeast.
Keywords
ChromatinEpigeneticsMulticellular organismBiologyTranscriptional regulationGeneticsComputational biologyCell biologyGeneTranscription factor
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Publication Info
- Year
- 1995
- Type
- book-chapter
- Pages
- 125-146
- Citations
- 13
- Access
- Closed
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Cite This
Lorraine Pillus,
Michael Grunstein
(1995).
Chromatin structure and epigenetic regulation in yeast.
, 125-146.
https://doi.org/10.1093/oso/9780199635764.003.0007
Identifiers
- DOI
- 10.1093/oso/9780199635764.003.0007