Abstract

In this retrospective study, chest CTs of 121 symptomatic patients infected with coronavirus disease-19 (COVID-19) from four centers in China from January 18, 2020 to February 2, 2020 were reviewed for common CT findings in relationship to the time between symptom onset and the initial CT scan (i.e. early, 0-2 days (36 patients), intermediate 3-5 days (33 patients), late 6-12 days (25 patients)). The hallmarks of COVID-19 infection on imaging were bilateral and peripheral ground-glass and consolidative pulmonary opacities. Notably, 20/36 (56%) of early patients had a normal CT. With a longer time after the onset of symptoms, CT findings were more frequent, including consolidation, bilateral and peripheral disease, greater total lung involvement, linear opacities, "crazy-paving" pattern and the "reverse halo" sign. Bilateral lung involvement was observed in 10/36 early patients (28%), 25/33 intermediate patients (76%), and 22/25 late patients (88%).

Keywords

MedicineHalo signCoronavirus disease 2019 (COVID-19)Retrospective cohort studyLungSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)CoronavirusRadiologyDiseasePeripheralComputed tomography2019-20 coronavirus outbreakInternal medicinePathologyInfectious disease (medical specialty)

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Year
2020
Type
article
Volume
295
Issue
3
Pages
200463-200463
Citations
2748
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Adam Bernheim, Xueyan Mei, Mingqian Huang et al. (2020). Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection. Radiology , 295 (3) , 200463-200463. https://doi.org/10.1148/radiol.2020200463

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DOI
10.1148/radiol.2020200463