Changes in Plasma HIV-1 RNA and CD4+ Lymphocyte Counts and the Risk of Progression to AIDS

Abstract

Treatment-induced changes in the plasma HIV-1 RNA level and the CD4+ lymphocyte count, taken together, are valid predictors of the clinical progression of HIV-related disease and can be used to assess the efficacy of zidovudine and possibly other antiretroviral drugs as well.

Keywords

MedicineZidovudineLymphocyteSidaInternal medicineBeta-2 microglobulinConfidence intervalImmunopathologyImmunologyGastroenterologyLentivirusViral diseaseHuman immunodeficiency virus (HIV)

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Publication Info

Year: 1996
Type: article
Volume: 334
Issue: 7
Pages: 426-431
Citations: 732
Access: Closed

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APA Style

                            
                                
                                    William A. O’Brien, 
                                
                                    Pamela Hartigan, 
                                
                                    David E. Martin
                                
                                et al.
                            
                            (1996). 
                            Changes in Plasma HIV-1 RNA and CD4+ Lymphocyte Counts and the Risk of Progression to AIDS. 
                            New England Journal of Medicine
                            , 334
                            (7)
                            , 426-431.
                            https://doi.org/10.1056/nejm199602153340703
                        

Identifiers

DOI: 10.1056/nejm199602153340703