Keywords
BiologyCell biologyProgrammed cell deathComputational biologyGeneticsApoptosis
Affiliated Institutions
Related Publications
Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution
Recent evidence indicates that a profound alteration in mitochondrial function constitutes an obligatory early event of the apoptotic process. The molecular mechanism accounting...
Apoptosis in the Pathogenesis and Treatment of Disease
In multicellular organisms, homeostasis is maintained through a balance between cell proliferation and cell death. Although much is known about the control of cell proliferation...
Interaction of CED-4 with CED-3 and CED-9: A Molecular Framework for Cell Death
Previous genetic studies of the nematode Caenorhabditis elegans identified three important components of the cell death machinery. CED-3 and CED-4 function to kill cells, wherea...
DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis
Inactivation of cell death is a major step in tumor development, and p53, a tumor suppressor frequently mutated in cancer, is a critical mediator of cell death. While a role for...
Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins
The loss of vital cells within healthy tissues contributes to the development, progression and treatment outcomes of many human disorders, including neurological and infectious ...
Publication Info
- Year
- 2004
- Type
- review
- Volume
- 116
- Issue
- 2
- Pages
- 205-219
- Citations
- 4600
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
4600
OpenAlex
Cite This
Nika N. Danial,
Stanley J. Korsmeyer
(2004).
Cell Death.
Cell
, 116
(2)
, 205-219.
https://doi.org/10.1016/s0092-8674(04)00046-7
Identifiers
- DOI
- 10.1016/s0092-8674(04)00046-7