Abstract

Extrapolation of this evidence of carcinogenesis from rodents to humans is an uncertain process. Longer-term clinical trials and careful postmarketing surveillance during the next several decades are needed to determine whether cholesterol-lowering drugs cause cancer in humans. In the meantime, the results of experiments in animals and humans suggest that lipid-lowering drug treatment, especially with the fibrates and statins, should be avoided except in patients at high short-term risk of coronary heart disease.

Keywords

MedicineClinical trialCarcinogenDrugPharmacologyCancerBioinformaticsInternal medicine

Affiliated Institutions

Related Publications

Publication Info

Year
1996
Type
letter
Volume
275
Issue
1
Pages
55-55
Citations
372
Access
Closed

External Links

Social Impact

Altmetric

Social media, news, blog, policy document mentions

Citation Metrics

372
OpenAlex

Cite This

Thomas B. Newman (1996). Carcinogenicity of Lipid-Lowering Drugs. JAMA , 275 (1) , 55-55. https://doi.org/10.1001/jama.1996.03530250059028

Identifiers

DOI
10.1001/jama.1996.03530250059028