Abstract

In patients with ST-segment elevation myocardial infarction who are undergoing primary PCI, anticoagulation with bivalirudin alone, as compared with heparin plus glycoprotein IIb/IIIa inhibitors, results in significantly reduced 30-day rates of major bleeding and net adverse clinical events. (ClinicalTrials.gov number, NCT00433966 [ClinicalTrials.gov].).

Keywords

BivalirudinMedicineConventional PCIPercutaneous coronary interventionMyocardial infarctionInternal medicineCardiologyHeparinStroke (engine)Adverse effectDirect thrombin inhibitorUnstable anginaAnginaAnesthesiaWarfarinAtrial fibrillationDabigatran

Affiliated Institutions

Related Publications

Publication Info

Year
2008
Type
article
Volume
358
Issue
21
Pages
2218-2230
Citations
1836
Access
Closed

External Links

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

1836
OpenAlex

Cite This

Gregg W. Stone, Bernhard Witzenbichler, Giulio Guagliumi et al. (2008). Bivalirudin during Primary PCI in Acute Myocardial Infarction. New England Journal of Medicine , 358 (21) , 2218-2230. https://doi.org/10.1056/nejmoa0708191

Identifiers

DOI
10.1056/nejmoa0708191