Abstract

Siderophores are natural iron chelators that have been evolutionarily selected to bind to Fe ions with very high binding constants. We utilize these unique properties to bind to metal oxide surfaces using a fragment of the cyanobacterial siderophore anachelin. The resulting poly(ethylene glycol) conjugate forms stable adlayers on TiO2 as has been shown by variable angle spectroscopic ellipsometry and X-ray photoelectron spectroscopy. Moreover, these coated surfaces are highly protein-resistant against the adsorption of full human serum.

Keywords

ChemistrySiderophoreChelationAdsorptionConjugateX-ray photoelectron spectroscopyMetalEthylene glycolCyanobacteriaIron oxideEllipsometryMetal ions in aqueous solutionInorganic chemistryChemical engineeringOrganic chemistryNanotechnologyBiochemistryBacteria

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Publication Info

Year
2006
Type
article
Volume
128
Issue
4
Pages
1064-1065
Citations
143
Access
Closed

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Cite This

Stefan Zürcher, David Wäckerlin, Yann Bethuel et al. (2006). Biomimetic Surface Modifications Based on the Cyanobacterial Iron Chelator Anachelin. Journal of the American Chemical Society , 128 (4) , 1064-1065. https://doi.org/10.1021/ja056256s

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DOI
10.1021/ja056256s