Abstract

Abstract Biocatalysis has found numerous applications in various fields as an alternative to chemical catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for pharmaceuticals as well for the flavors and fragrance industry, are the most prominent examples. In addition, biocatalysts are used on a large scale to make specialty and even bulk chemicals. This review intends to give illustrative examples in this field with a special focus on scalable chemical production using enzymes. It also discusses the opportunities and limitations of enzymatic syntheses using distinct examples and provides an outlook on emerging enzyme classes.

Keywords

BiocatalysisBiochemical engineeringSpeciality chemicalsOrganic synthesisScalabilityScale (ratio)Fine chemicalChemistryNanotechnologyCatalysisComputer scienceManagement scienceOrganic chemistryEngineeringMaterials scienceIonic liquidPhysics

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Publication Info

Year
2020
Type
review
Volume
60
Issue
1
Pages
88-119
Citations
1262
Access
Closed

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Shuke Wu, Radka Šnajdrová, Jeffrey C. Moore et al. (2020). Biocatalysis: Enzymatic Synthesis for Industrial Applications. Angewandte Chemie International Edition , 60 (1) , 88-119. https://doi.org/10.1002/anie.202006648

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DOI
10.1002/anie.202006648