Association Between Iron Overload and the Risk of Ocular Hypertension, Primary Open-Angle Glaucoma, and Normal-Tension Glaucoma

Abstract

Our findings suggest that patients with iron overload may benefit from targeted ophthalmologic referral, particularly those with visual symptoms or additional risk factors. The association between iron dysregulation and glaucoma highlights opportunities for interdisciplinary care, risk stratification using ferritin, and mechanistic research into ferroptosis-driven neurodegeneration, with implications for iron-targeted neuroprotective strategies.

Affiliated Institutions

• National Chiayi University TW
• National Yang Ming Chiao Tung University TW
• China Medical University Hospital TW
• Tunghai University TW
• Taipei City Hospital TW
• Far Eastern Memorial Hospital TW
• Brown University US
• National Chung Hsing University TW
• Taichung Veterans General Hospital TW
• China Medical University TW
• Ministry of Health and Welfare TW
• National Taiwan University Hospital TW
• University of Taipei TW
• Fu Jen Catholic University TW

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