Abstract

This FAIRsharing record describes: APID Interactomes (Agile Protein Interactomes DataServer) provides information on the protein interactomes of numerous organisms, based on the integration of known experimentally validated protein-protein physical interactions (PPIs). The interactome data includes a report on quality levels and coverage over the proteomes for each organism included. APID integrates PPIs from primary databases of molecular interactions (BIND, BioGRID, DIP, HPRD, IntAct, MINT) and also from experimentally resolved 3D structures (PDB) where more than two distinct proteins have been identified. This collection references protein interactors, through a UniProt identifier.

Keywords

BiologyProtein–protein interactionComputational biologyProteomeInteractomeWeb serverComputer scienceBioinformaticsThe InternetGeneticsGeneWorld Wide Web

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The UniProt knowledgebase is a large resource of protein sequences and associated detailed annotation. The database contains over 60 million sequences, of which over half a mill...

2016 Nucleic Acids Research 4500 citations

Publication Info

Year
2016
Type
article
Volume
44
Issue
W1
Pages
W529-W535
Citations
116
Access
Closed

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Diego Alonso‐López, Miguel A. Gutiérrez, Kátia de Paiva Lopes et al. (2016). APID interactomes: providing proteome-based interactomes with controlled quality for multiple species and derived networks. Nucleic Acids Research , 44 (W1) , W529-W535. https://doi.org/10.1093/nar/gkw363

Identifiers

DOI
10.1093/nar/gkw363