Antitumor activity of trastuzumab in combination with chemotherapy in human gastric cancer xenograft models

Kaori Fujimoto-Ouchi; Fumiko Sekiguchi; Hideyuki Yasuno; Yoichiro Moriya; Kazushige Mori; Yutaka Tanaka

doi:10.1007/s00280-006-0337-z

Keywords

TrastuzumabDocetaxelCapecitabineCancerPaclitaxelMedicineCisplatinBreast cancerCancer researchCancer cellImmunohistochemistryPharmacologyChemotherapyInternal medicineColorectal cancer

Related Publications

Gefitinib in Combination With Paclitaxel and Carboplatin in Advanced Non–Small-Cell Lung Cancer: A Phase III Trial—INTACT 2

Roy S. Herbst , Giuseppe Giaccone , Joan H. Schiller +14 more

Purpose Preclinical studies indicate that gefitinib (Iressa, ZD1839; AstraZeneca, Wilmington, DE), an orally active epidermal growth factor receptor tyrosine kinase inhibitor, m...

2004 Journal of Clinical Oncology 1714 citations

Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer

Shanu Modi , Cristina Saura , Toshinari Yamashita +22 more

Trastuzumab deruxtecan showed durable antitumor activity in a pretreated patient population with HER2-positive metastatic breast cancer. In addition to nausea and myelosuppressi...

2019 New England Journal of Medicine 1788 citations

Assessment of a HER2 scoring system for gastric cancer: results from a validation study

Manfred Hofmann , Oliver Stoß , Di Shi +6 more

Aims: Human epidermal growth factor receptor 2 (HER2) overexpression/amplification is implicated in the development of various solid tumour types. Validated methods and scoring ...

2008 Histopathology 1169 citations

Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery.

John W. Park , Keelung Hong , Dmitri B. Kirpotin +9 more

Anti-HER2 immunoliposomes produced enhanced antitumor efficacy via targeted delivery.

2002 PubMed 648 citations

Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2

Dennis J. Slamon , Brian Leyland‐Jones , Steven Shak +9 more

Trastuzumab increases the clinical benefit of first-line chemotherapy in metastatic breast cancer that overexpresses HER2.

2001 New England Journal of Medicine 11312 citations

Publication Info

Year: 2006
Type: article
Volume: 59
Issue: 6
Pages: 795-805
Citations: 192
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Antitumor activity of trastuzumab in combination with chemotherapy in human gastric cancer xenograft models

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

192

OpenAlex

Cite This

APA Style

                            
                                
                                    Kaori Fujimoto-Ouchi, 
                                
                                    Fumiko Sekiguchi, 
                                
                                    Hideyuki Yasuno
                                
                                et al.
                            
                            (2006). 
                            Antitumor activity of trastuzumab in combination with chemotherapy in human gastric cancer xenograft models. 
                            Cancer Chemotherapy and Pharmacology
                            , 59
                            (6)
                            , 795-805.
                            https://doi.org/10.1007/s00280-006-0337-z
                        

Identifiers

DOI: 10.1007/s00280-006-0337-z