Antimicrobial Resistance in ESKAPE Pathogens

David M. P. De Oliveira; Brian M. Forde; Timothy J. Kidd; Patrick N. A. Harris; Mark A. Schembri; Scott A. Beatson; David L. Paterson; Mark J. Walker

doi:10.1128/cmr.00181-19

Abstract

Antimicrobial-resistant ESKAPE ( E nterococcus faecium , S taphylococcus aureus , K lebsiella pneumoniae , A cinetobacter baumannii , P seudomonas aeruginosa , and E nterobacter species) pathogens represent a global threat to human health. The acquisition of antimicrobial resistance genes by ESKAPE pathogens has reduced the treatment options for serious infections, increased the burden of disease, and increased death rates due to treatment failure and requires a coordinated global response for antimicrobial resistance surveillance.

Keywords

AntimicrobialAntibiotic resistanceMicrobiologyKlebsiella pneumoniaeDrug resistanceBiologyMedicineAntibioticsGeneEscherichia coli

MeSH Terms

Anti-Bacterial AgentsBacteriaBacterial InfectionsDrug DiscoveryDrug ResistanceMultipleBacterialHumans

Affiliated Institutions

The University of Queensland AU

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Publication Info

Year: 2020
Type: review
Volume: 33
Issue: 3
Citations: 1848
Access: Closed

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APA Style

                            
                                
                                    David M. P. De Oliveira, 
                                
                                    Brian M. Forde, 
                                
                                    Timothy J. Kidd
                                
                                et al.
                            
                            (2020). 
                            Antimicrobial Resistance in ESKAPE Pathogens. 
                            Clinical Microbiology Reviews
                            , 33
                            (3)
                            .
                            https://doi.org/10.1128/cmr.00181-19
                        

Identifiers

DOI: 10.1128/cmr.00181-19
PMID: 32404435
PMCID: PMC7227449

Data Quality

Data completeness: 90%