Abstract
Thromboembolic prophylaxis of women with mechanical heart valves during pregnancy is best achieved with OA; however, this increases the risk of fetal embryopathy. Substituting OA with heparin between 6 and 12 weeks reduces the risk of fetopathic effects, but with an increased risk of thromboembolic complications. The use of low-dose heparin is definitely inadequate; the use of adjusted-dose heparin warrants aggressive monitoring and appropriate dose adjustment. Large prospective trials to determine the best regimen for these women are needed.
Keywords
MedicinePregnancyAbortionObstetricsWarfarinHeparinRegimenGestationFetusSurgeryInternal medicineAtrial fibrillation
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Publication Info
- Year
- 2000
- Type
- review
- Volume
- 160
- Issue
- 2
- Pages
- 191-191
- Citations
- 742
- Access
- Closed
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Cite This
Wee‐Shian Chan,
Sonia S. Anand,
Jeffrey S. Ginsberg
(2000).
Anticoagulation of Pregnant Women With Mechanical Heart Valves.
Archives of Internal Medicine
, 160
(2)
, 191-191.
https://doi.org/10.1001/archinte.160.2.191
Identifiers
- DOI
- 10.1001/archinte.160.2.191