Abstract

The advent of multidrug resistance among pathogenic bacteria is imperiling the worth of antibiotics, which have previously transformed medical sciences. The crisis of antimicrobial resistance has been ascribed to the misuse of these agents and due to unavailability of newer drugs attributable to exigent regulatory requirements and reduced financial inducements. Comprehensive efforts are needed to minimize the pace of resistance by studying emergent microorganisms, resistance mechanisms, and antimicrobial agents. Multidisciplinary approaches are required across health care settings as well as environment and agriculture sectors. Progressive alternate approaches including probiotics, antibodies, and vaccines have shown promising results in trials that suggest the role of these alternatives as preventive or adjunct therapies in future.

Keywords

Antibiotic resistanceAntibioticsIntensive care medicinePaceUnavailabilityAntimicrobialMedicineResistance (ecology)Multiple drug resistanceBusinessBiotechnologyRisk analysis (engineering)BiologyMicrobiologyEngineering

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Publication Info

Year
2018
Type
review
Volume
Volume 11
Pages
1645-1658
Citations
2408
Access
Closed

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Social media, news, blog, policy document mentions

Citation Metrics

2408
OpenAlex
39
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1956
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Cite This

Bilal Aslam, Wei Wang, Muhammad Arshad et al. (2018). Antibiotic resistance: a rundown of a global crisis. Infection and Drug Resistance , Volume 11 , 1645-1658. https://doi.org/10.2147/idr.s173867

Identifiers

DOI
10.2147/idr.s173867
PMID
30349322
PMCID
PMC6188119

Data Quality

Data completeness: 81%