Analysis of Gene Diversity in Subdivided Populations

1973 Proceedings of the National Academy of Sciences 8,825 citations

Abstract

A method is presented by which the gene diversity (heterozygosity) of a subdivided population can be analyzed into its components, i.e., the gene diversities within and between subpopulations. This method is applicable to any population without regard to the number of alleles per locus, the pattern of evolutionary forces such as mutation, selection, and migration, and the reproductive method of the organism used. Measures of the absolute and relative magnitudes of gene differentiation among subpopulations are also proposed.

Keywords

Loss of heterozygosityBiologyLocus (genetics)GeneticsAlleleGeneEvolutionary biologyPopulationGene poolGenetic diversityPopulation geneticsSelection (genetic algorithm)Allele frequencyDemography

Affiliated Institutions

Related Publications

Genetic Distance between Populations

A measure of genetic distance (D) based on the identity of genes between populations is formulated. It is defined as D = -logeI, where I is the normalized identity of genes betw...

1972 The American Naturalist 9733 citations

Publication Info

Year
1973
Type
article
Volume
70
Issue
12
Pages
3321-3323
Citations
8825
Access
Closed

External Links

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

8825
OpenAlex

Cite This

Masatoshi Nei (1973). Analysis of Gene Diversity in Subdivided Populations. Proceedings of the National Academy of Sciences , 70 (12) , 3321-3323. https://doi.org/10.1073/pnas.70.12.3321

Identifiers

DOI
10.1073/pnas.70.12.3321