An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules

Amrita Basu; Nicole E. Bodycombe; Jaime H. Cheah; Edmund V. Price; Ke Liu; Giannina I. Schaefer; Richard Y. Ebright; Michelle L. Stewart; Daisuke Ito; Stephanie Wang; Abigail Bracha; Ted Liefeld; Mathias J. Wawer; Joshua C. Gilbert; Andrew J. Wilson; Nicolas Stransky; Gregory V. Kryukov; Vlado Dančík; Jordi Barretina; Levi A. Garraway; C. Suk-Yee Hon; Benito Muñoz; Joshua A. Bittker; Brent R. Stockwell; Dineo Khabele; Andrew M. Stern; Paul A. Clemons; Alykhan F. Shamji; Stuart L. Schreiber

doi:10.1016/j.cell.2013.08.003

Keywords

BiologyLineage (genetic)Computational biologyResource (disambiguation)Evolutionary biologyGeneticsGeneComputer science

Affiliated Institutions

Related Publications

Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery

Nicholas Ekow Thomford , Dimakatso Alice Senthebane , Arielle Rowe +4 more

The therapeutic properties of plants have been recognised since time immemorial. Many pathological conditions have been treated using plant-derived medicines. These medicines ar...

2018 International Journal of Molecular Sc... 1143 citations

ConsensusPathDB 2022: molecular interactions update as a resource for network biology

Atanas Kamburov , Ralf Herwig

Abstract Molecular interactions are key drivers of biological function. Providing interaction resources to the research community is important since they allow functional interp...

2021 Nucleic Acids Research 93 citations

Updates in Rhea – an expert curated resource of biochemical reactions

Anne Morgat , Thierry Lombardot , Kristian B. Axelsen +13 more

Rhea (http://www.rhea-db.org) is a comprehensive and non-redundant resource of expert-curated biochemical reactions designed for the functional annotation of enzymes and the des...

2016 Nucleic Acids Research 69 citations

PocketQuery: protein-protein interaction inhibitor starting points from protein-protein interaction structure

David Ryan Koes , Carlos J. Camacho

PocketQuery (http://pocketquery.csb.pitt.edu) is a web interface for exploring the properties of protein-protein interaction (PPI) interfaces with a focus on the discovery of pr...

2012 Nucleic Acids Research 89 citations

Antibiotics: past, present and future

Matthew I. Hutchings , Andrew W. Truman , Barrie Wilkinson

The first antibiotic, salvarsan, was deployed in 1910. In just over 100 years antibiotics have drastically changed modern medicine and extended the average human lifespan by 23 ...

2019 Current Opinion in Microbiology 2070 citations

Publication Info

Year: 2013
Type: article
Volume: 154
Issue: 5
Pages: 1151-1161
Citations: 827
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

827

OpenAlex

Cite This

APA Style

                            
                                
                                    Amrita Basu, 
                                
                                    Nicole E. Bodycombe, 
                                
                                    Jaime H. Cheah
                                
                                et al.
                            
                            (2013). 
                            An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules. 
                            Cell
                            , 154
                            (5)
                            , 1151-1161.
                            https://doi.org/10.1016/j.cell.2013.08.003
                        

Identifiers

DOI: 10.1016/j.cell.2013.08.003