An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar

Nathan D. Grubaugh; Karthik Gangavarapu; Joshua Quick; Nathaniel L. Matteson; Jaqueline Góes de Jesus; Bradley J. Main; Amanda L. Tan; Lauren M. Paul; Doug E. Brackney; Saran Grewal; Nikos Gurfield; Koen K. A. Van Rompay; Sharon Isern; Scott F. Michael; Lark L. Coffey; Nicholas J. Loman; Kristian G. Andersen

doi:10.1186/s13059-018-1618-7

Keywords

BiologyAmpliconGenetic diversityComputational biologyDeep sequencingVirusEvolutionary biologyGeneticsGenomeGenePolymerase chain reactionPopulation

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Publication Info

Year: 2019
Type: article
Volume: 20
Issue: 1
Pages: 8-8
Citations: 1064
Access: Closed

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APA Style

                            
                                
                                    Nathan D. Grubaugh, 
                                
                                    Karthik Gangavarapu, 
                                
                                    Joshua Quick
                                
                                et al.
                            
                            (2019). 
                            An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar. 
                            Genome biology
                            , 20
                            (1)
                            , 8-8.
                            https://doi.org/10.1186/s13059-018-1618-7
                        

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DOI: 10.1186/s13059-018-1618-7