Amyloid: Toward terminology clarification Report from the Nomenclature Committee of the International Society of Amyloidosis

Abstract

The modern nomenclature of amyloidosis now includes 25 human and 8 animal fibril proteins. To be included in the list, the protein has to be a major fibril protein in extracellular deposits, which have the characteristics of amyloid, including affinity for Congo red with resulting green birefringence. Synthetic fibrils with amyloid properties are best named 'amyloid-like'. With increasing knowledge, however, the borders between different protein aggregates tend to become less sharp.

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Affiliated Institutions

• Indiana University – Purdue University Indianapolis US
• Uppsala University SE
• Istituti di Ricovero e Cura a Carattere Scientifico IT
• New York University US
• The University of Melbourne AU
• Indiana University School of Medicine
• Scripps Research Institute US
• Ōtani University JP
• Instituto de Biologia Molecular e Celular
• National Institutes of Health US

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