Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Vassilis G. Gorgoulis; Leandros-Vassilios Vassiliou; Panagiotis Karakaidos; Panayotis Zacharatos; Athanassios Kotsinas; Triantafillos Liloglou; Monica Venere; Richard A. DiTullio; Nikolaos G. Kastrinakis; Brynn Levy; Dimitris Kletsas; Akihiro Yoneta; Meenhard Herlyn; Christos Kittas; Thanos D. Halazonetis

doi:10.1038/nature03485

Keywords

DNA damageGenome instabilityDNA repairBiologyG2-M DNA damage checkpointHistoneDNAMolecular biologyCancer researchDNA replicationChromosome instabilityChromosomal fragile siteCell cycle checkpointMutationApoptosisGeneCell cycleGenetics

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Publication Info

Year: 2005
Type: article
Volume: 434
Issue: 7035
Pages: 907-913
Citations: 1975
Access: Closed

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APA Style

                            
                                
                                    Vassilis G. Gorgoulis, 
                                
                                    Leandros-Vassilios Vassiliou, 
                                
                                    Panagiotis Karakaidos
                                
                                et al.
                            
                            (2005). 
                            Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. 
                            Nature
                            , 434
                            (7035)
                            , 907-913.
                            https://doi.org/10.1038/nature03485
                        

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DOI: 10.1038/nature03485