A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade

Daniela S. Thommen; Viktor H. Koelzer; Petra Herzig; Andreas Roller; Marcel P. Trefny; Sarah Dimeloe; Anna Kiialainen; Jonathan Hanhart; Catherine Schill; Christoph Hess; Spasenija Savic Prince; Mark Wiese; Didier Lardinois; Ping‐Chih Ho; Christian Klein; Vaios Karanikas; Kirsten D. Mertz; Ton N. Schumacher; Alfred Zippelius

doi:10.1038/s41591-018-0057-z

Keywords

CD8PD-L1BiologyImmune systemBlockadeImmunologyCancer researchT cellCytotoxic T cellLung cancerCytokineCancerCellImmunotherapyReceptorMedicineInternal medicineGenetics

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Publication Info

Year: 2018
Type: article
Volume: 24
Issue: 7
Pages: 994-1004
Citations: 1123
Access: Closed

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APA Style

                            
                                
                                    Daniela S. Thommen, 
                                
                                    Viktor H. Koelzer, 
                                
                                    Petra Herzig
                                
                                et al.
                            
                            (2018). 
                            A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade. 
                            Nature Medicine
                            , 24
                            (7)
                            , 994-1004.
                            https://doi.org/10.1038/s41591-018-0057-z
                        

Identifiers

DOI: 10.1038/s41591-018-0057-z