A mew computer method for the storage and manipulation of DNA gel reading data

1980 Nucleic Acids Research 681 citations

Abstract

This paper describes a new way of storing DNA gel reading data and an accompanying set of computer programs. These programs will perform all the manipulations that are required on data gained by the so-called 'shotgun' method of DNA sequencing. This system simplifies the computer processing involved with this sequencing method and also has the capability of being able at any time during a project to display, lined up in register, all the gel reading covering any section of the sequence.

Keywords

BiologyReading (process)ShotgunShotgun sequencingSet (abstract data type)DNADNA sequencingReading frameFragment (logic)Computer scienceComputational biologyComputer hardwareGeneticsOpen reading frameProgramming languagePeptide sequenceGene

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Publication Info

Year
1980
Type
article
Volume
8
Issue
16
Pages
3673-3694
Citations
681
Access
Closed

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Cite This

Rodger Staden (1980). A mew computer method for the storage and manipulation of DNA gel reading data. Nucleic Acids Research , 8 (16) , 3673-3694. https://doi.org/10.1093/nar/8.16.3673

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DOI
10.1093/nar/8.16.3673