Abstract
Evidence for an independent role of increased physical activity in the primary prevention of coronary heart disease has grown in recent years. The authors apply the techniques of meta-analysis to data extracted from the published literature by Powell et al. (Ann Rev Public Health 1987;8:253-87), as well as more recent studies addressing this relation, in order to make formal quantitative statements and to explore features of study design that influence the observed relation between physical activity and coronary heart disease risk. They find, for example, a summary relative risk of death from coronary heart disease of 1.9 (95% confidence interval 1.6-2.2) for sedentary compared with active occupations. The authors also find that methodologically stronger studies tend to show a larger benefit of physical activity than less well-designed studies.
Keywords
Affiliated Institutions
Related Publications
Physical Activity and All-cause Mortality: An Updated Meta-analysis with Different Intensity Categories
In a meta-analysis we investigated the effect of physical activity with different intensity categories on all-cause mortality. Many studies have reported positive effects of reg...
Physical activity and risk of coronary heart disease in India
Leisure-time exercise, including as much as 35-40 minutes per day of brisk walking, was protective for CHD risk and sedentary lifestyles were positively associated with risk of ...
Sedentary Behavior, Exercise, and Cardiovascular Health
Sedentary behavior and physical inactivity are among the leading modifiable risk factors worldwide for cardiovascular disease and all-cause mortality. The promotion of physical ...
Revisiting Rose: strategies for reducing coronary heart disease
The way we assess risk of coronary heart disease has become more accurate in recent years. How does this affect the efficacy of primary and secondary prevention strategies?
Dose Response Between Physical Activity and Risk of Coronary Heart Disease
Background No reviews have quantified the specific amounts of physical activity required for lower risks of coronary heart disease when assessing the dose-response relation. Ins...
Publication Info
- Year
- 1990
- Type
- review
- Volume
- 132
- Issue
- 4
- Pages
- 612-628
- Citations
- 1398
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1093/oxfordjournals.aje.a115704