Abstract

C-H activation has surfaced as an increasingly powerful tool for molecular sciences, with notable applications to material sciences, crop protection, drug discovery, and pharmaceutical industries, among others. Despite major advances, the vast majority of these C-H functionalizations required precious 4d or 5d transition metal catalysts. Given the cost-effective and sustainable nature of earth-abundant first row transition metals, the development of less toxic, inexpensive 3d metal catalysts for C-H activation has gained considerable recent momentum as a significantly more environmentally-benign and economically-attractive alternative. Herein, we provide a comprehensive overview on first row transition metal catalysts for C-H activation until summer 2018.

Keywords

ChemistryTransition metalEnvironmental chemistryOrganic chemistryCatalysis

Affiliated Institutions

Related Publications

Photoredox Catalysis with Visible Light

Kirsten Zeitler

On the sunny side: Recent examples of visible-light-promoted photoredox catalysis in the presence of [Ru(bpy)3]2+ as an efficient photocatalyst have set new standards for conduc...

2009 Angewandte Chemie International Edition 973 citations

Publication Info

Year
2018
Type
review
Volume
119
Issue
4
Pages
2192-2452
Citations
2163
Access
Closed

External Links

Download PDF (Free) View on DOI.org PubMed Semantic Scholar

Social Impact

Altmetric
PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

2163
OpenAlex
3
Influential
2101
CrossRef

Cite This

Parthasarathy Gandeepan, Thomas Müller, Daniel Zell et al. (2018). 3d Transition Metals for C–H Activation. Chemical Reviews , 119 (4) , 2192-2452. https://doi.org/10.1021/acs.chemrev.8b00507

Identifiers

DOI
10.1021/acs.chemrev.8b00507
PMID
30480438

Data Quality

Data completeness: 81%