Abstract

The benefits of exercise training in the prevention and treatment of insulin resistance, impaired glucose homeostasis, and NIDDM are strongly supported by current research. The actual mechanisms involved have not been completely identified but occur at the systemic, tissue, and cellular levels. The adaptations that are responsible for the prophylactic effects of exercise training, however, start to subside rapidly once training ceases and are completely lost within 1 to 2 weeks of detraining [4, 17, 37, 68, 161]. Thus, the benefits of exercise training must be renewed on a regular basis. In addition, many of the systemic and cellular adaptations that are responsible for an improved skeletal muscle insulin action occur in only those muscles involved in the training program [4, 28]. Therefore, exercise training programs that consist of various modes of exercise, and which require the use of a large muscle mass, such as swimming, power walking, and strength training, may be the most advantageous for the prevention and treatment of insulin resistance and associated diseases.

Keywords

Insulin resistanceDiabetes mellitusMedicineInsulinResistance trainingSkeletal musclePhysical medicine and rehabilitationPhysical exerciseHomeostasisStrength trainingEndocrinologyInternal medicineBioinformaticsPhysical therapyBiology

Affiliated Institutions

Related Publications

Publication Info

Year
1999
Type
review
Volume
27
Pages
1???36-1???36
Citations
194
Access
Closed

External Links

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

194
OpenAlex

Cite This

John L. Ivy, Ted W. Zderic, Donovan L. Fogt (1999). 1 Prevention and Treatment of Non-Insulin-Dependent Diabetes Mellitus. Exercise and Sport Sciences Reviews , 27 , 1???36-1???36. https://doi.org/10.1249/00003677-199900270-00003

Identifiers

DOI
10.1249/00003677-199900270-00003