Universitat Pompeu Fabra

Sarcopenia: revised European consensus on definition and diagnosis

EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat pati...

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

We report the generation and analysis of functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of the pilot phase of the ENCO...

The repertoire of mutational signatures in human cancer

The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Correspondence Analysis in Practice

Preface Scatterplots and Maps Profiles and the Profile Space Masses and Centroids Chi-Square Distance and Inertia Plotting Chi-Square Distances Reduction of Dimensionality Optim...

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

Improving the Assessment of the Outcome of Nonsynonymous SNVs with a Consensus Deleteriousness Score, Condel

A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial–mesenchymal transition

Expression of Snail1 in epithelial cells triggers an epithelial–mesenchymal transition (EMT). Here, we demonstrate that the synthesis of Zeb2, a transcriptional repressor of E-c...