Can Animal Models of Disease Reliably Inform Human Studies?
H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials.
Publications
View AllPublication Bias in Reports of Animal Stroke Studies Leads to Major Overstatement of Efficacy
The consolidation of scientific knowledge proceeds through the interpretation and then distillation of data presented in research reports, first in review articles and then in t...
Good Laboratory Practice
Background and Purpose— As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve ...
Pretreatment Diffusion- and Perfusion-MR Lesion Volumes Have a Crucial Influence on Clinical Response to Stroke Thrombolysis
We hypothesized that pretreatment magnetic resonance imaging (MRI) diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) lesion volumes may have influenced clini...
Institution Info
- Type
- nonprofit
- Country
- AU
- Publications
- 4
- Citations
- 2,331
External Links
Identifiers
- ROR
- https://ror.org/004ckc033