Institute for Clinical Evaluative Sciences

AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both

The number of published systematic reviews of studies of healthcare interventions has increased rapidly and these are used extensively for clinical and policy decisions. Systema...

A pragmatic–explanatory continuum indicator summary (PRECIS): a tool to help trial designers

Will evidence-based nursing practice make practice perfect?

Evidence-based practice, or evidence-based decision-making, is rapidly developing as a growth industry in nursing and the health professions more widely. It has its origins in t...

Revisiting Rose: strategies for reducing coronary heart disease

The way we assess risk of coronary heart disease has become more accurate in recent years. How does this affect the efficacy of primary and secondary prevention strategies?