Frederick National Laboratory for Cancer Research

Remdesivir for the Treatment of Covid-19 — Final Report

Our data show that remdesivir was superior to placebo in shortening the time to recovery in adults who were hospitalized with Covid-19 and had evidence of lower respiratory trac...

DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)

Abstract DAVID is a popular bioinformatics resource system including a web server and web service for functional annotation and enrichment analyses of gene lists. It consists of...

Comparative Genomics of the Eukaryotes

A comparative analysis of the genomes of Drosophila melanogaster , Caenorhabditis elegans , and Saccharomyces cerevisiae —and the proteins they are predicted to encode—was under...

APOBEC3B is an enzymatic source of mutation in breast cancer

Methods for High-Density Admixture Mapping of Disease Genes

Chromosomal Inheritance of Epigenetic States in Fission Yeast During Mitosis and Meiosis

Scalable, cGMP‐compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL‐15/lactadherin complexes

ABSTRACT The development of extracellular vesicles (EV) for therapeutic applications is contingent upon the establishment of reproducible, scalable, and high‐throughput methods ...

Protein-Protein Interfaces: Architectures and Interactions in Protein-Protein Interfaces and in Protein Cores. Their Similarities and Differences

Protein structures generally consist of favorable folding motifs formed by specific arrangements of secondary structure elements. Similar architectures can be adopted by differe...

Excess information at bacteriophage T7 genomic promoters detected by a random cloning technique

In our previous analysis of the information at binding sites on nucleic acids, we found that most of the sites examined contain the amount of information expected from their fre...