Xiangju Kong - Researcher Profile | RDL Research Database

Publications

3 shown

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

Ramin Nazarian , Hubing Shi , Qi Wang +13 more

Activating B-RAF(V600E) (also known as BRAF) kinase mutations occur in ∼7% of human malignancies and ∼60% of melanomas. Early clinical experience with a novel clas...

2010 Nature 2132 citations

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

Jesse M. Zaretsky , Ángel García-Díaz , Daniel Sanghoon Shin +26 more

In this study, acquired resistance to PD-1 blockade immunotherapy in patients with melanoma was associated with defects in the pathways involved in interferon-receptor signaling...

2016 New England Journal of Medicine 2998 citations

Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma

Willy Hugo , Jesse M. Zaretsky , Lu ming Sun +15 more

2017 Cell 475 citations

Frequent Co-Authors

Researcher Info

h-index: 3
Publications: 3
Citations: 5,605
Institution: UCLA Jonsson Comprehensive Cancer Center

External Links

Google Scholar

Impact Metrics

h-index 3

h-index: Number of publications with at least h citations each.