Extracellular vesicles: Exosomes, microvesicles, and friends
Cells release into the extracellular environment diverse types of membrane vesicles of endosomal and plasma membrane origin called exosomes and microvesicles, respectively. Thes...
Publications
7 shownMHC II in Dendritic Cells is Targeted to Lysosomes or T Cell‐Induced Exosomes Via Distinct Multivesicular Body Pathways
Dendritic cells (DCs) express major histocompatibility complex class II (MHC II) to present peptide antigens to T cells. In immature DCs, which bear low cell surface levels of M...
MHC class II‐associated proteins in B‐cell exosomes and potential functional implications for exosome biogenesis
Professional antigen‐presenting cells secrete major histocompatibility complex class II (MHC II) carrying exosomes with unclear physiological function(s). Exosomes are first gen...
Identification of Distinct Populations of Prostasomes That Differentially Express Prostate Stem Cell Antigen, Annexin A1, and GLIPR2 in Humans1
In addition to sperm cells, seminal fluid contains various small membranous vesicles. These include prostasomes, membrane vesicles secreted by prostate epithelial cells. Prostas...
Selective Enrichment of Tetraspan Proteins on the Internal Vesicles of Multivesicular Endosomes and on Exosomes Secreted by Human B-lymphocytes
Association of major histocompatibility complex (MHC) class II molecules with peptides occurs in a series of endocytic vacuoles, termed MHC class II-enriched compartments (MIICs...
Biological properties of extracellular vesicles and their physiological functions
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of intercellular communication, both in prokaryotes and eukaryotes. This is due to their...
B lymphocytes secrete antigen-presenting vesicles.
Antigen-presenting cells contain a specialized late endocytic compartment, MIIC (major histocompatibility complex [MHC] class II-enriched compartment), that harbors newly synthe...
Frequent Co-Authors
Researcher Info
- h-index
- 7
- Publications
- 7
- Citations
- 18,806
- Institution
- Utrecht University
External Links
Identifiers
- ORCID
- 0000-0001-6782-2541
Impact Metrics
h-index
7
h-index: Number of publications with at least h citations each.