Publications
12 shownClonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
Most patients with acute myeloid leukaemia (AML) die from progressive disease after relapse, which is associated with clonal evolution at the cytogenetic level. To determine the...
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole-genome sequencing of 12 ETP ALL cases and...
Evolution of Symbiotic Bacteria in the Distal Human Intestine
The adult human intestine contains trillions of bacteria, representing hundreds of species and thousands of subspecies. Little is known about the selective pressures that have s...
Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome
By comparing the sequences of tumor and skin genomes of a patient with AML-M1, we have identified recurring mutations that may be relevant for pathogenesis.
Frequent Co-Authors
Researcher Info
- h-index
- 12
- Publications
- 12
- Citations
- 53,802
- Institution
- Washington University in St. Louis
External Links
Identifiers
- ORCID
- 0000-0002-1992-1358
Impact Metrics
h-index: Number of publications with at least h citations each.