Richard K. Wilson

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Comprehensive molecular portraits of human breast tumours

Integrated genomic characterization of endometrial carcinoma

A global reference for human genetic variation

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

Most patients with acute myeloid leukaemia (AML) die from progressive disease after relapse, which is associated with clonal evolution at the cytogenetic level. To determine the...

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole-genome sequencing of 12 ETP ALL cases and...

The genomic landscape of hypodiploid acute lymphoblastic leukemia

BreakDancer: an algorithm for high-resolution mapping of genomic structural variation

A map for sequence analysis of the Arabidopsis thaliana genome

Evolution of Symbiotic Bacteria in the Distal Human Intestine

The adult human intestine contains trillions of bacteria, representing hundreds of species and thousands of subspecies. Little is known about the selective pressures that have s...

Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome

By comparing the sequences of tumor and skin genomes of a patient with AML-M1, we have identified recurring mutations that may be relevant for pathogenesis.